TY  - JOUR
TI  - Head-tail patterning of the vertebrate embryo: one, two or many unresolved problems?
AU  - Stern, ClaudioD.
AU  - Charite, Jeroen
AU  - Deschamps, Jacqueline
AU  - Duboule, Denis
AU  - Durston, AnthonyJ.
AU  - Kmita, Marie
AU  - Nicolas, Jean-Francois
AU  - Palmeirim, Isabel
AU  - Smith, JimC.
AU  - Wolpert, Lewis
T2  - The International Journal of Developmental Biology
AB  - When, where and how is the head-tail axis of the embryo set up during development? These are such fundamental and intensely studied questions that one might expect them to have been answered long ago. Not so; we still understand very little about the cellular or molecular mechanisms that lead to the orderly arrangement of body elements along the head-tail axis in vertebrates. In this paper, we outline some of the major outstanding problems and controversies and try to identify some reasons why it has been so difficult to resolve this important issue.
PY  - 2006
DO  - 10.1387/ijdb.052095cs
VL  - 50
IS  - 1
SP  - 3
EP  - 15
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/052095cs
Y2  - 2024/11/21/23:47:29
ER  -