TY - JOUR TI - Morphogenesis, plasticity and irreversibility AU - Furusawa, Chikara AU - Kaneko, Kunihiko T2 - The International Journal of Developmental Biology AB - The dynamical systems theory of morphogenesis is surveyed, in which positional information is generated through intracellular reaction dynamics and cellĀ­cell interaction. Cells differentiate because of these dynamics. In addition, these differentiated cells form an ordered spatial pattern, which further stabilizes the cellular states, leading to robust morphogenesis and irreversibility in the differentiation. Induction, community effect, gastrulation and activin-controlled artificial tissue-genesis are discussed from the perspective of this theory and the relevance of dynamics of cellular plasticity is stressed. PY - 2006 DO - 10.1387/ijdb.052051cf VL - 50 IS - 2-3 SP - 223 EP - 232 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/052051cf Y2 - 2024/11/21/17:03:59 ER -