TY - JOUR TI - Single-cell transcriptional profiles and spatial patterning of the mammalian olfactory epithelium AU - Tietjen, Ian AU - Rihel, Jason AU - Dulac, CatherineG. T2 - The International Journal of Developmental Biology AB - In order to gain insights into the regulatory control of neuronal diversity in the mammalian olfactory system, we have identified the transcriptional profile of individual olfactory neurons. A single cell microarray strategy was performed to search for candidate genes involved in the molecular specification of dorso-ventral zones of olfactory receptor (OR) expression. Several transcripts were identified that display differential expression in distinct OR zones, including a novel family of genes, the Lozenge-like (Lzl) genes which share sequence consensus motifs with Lozenge, a transcription factor involved in the patterning of the Drosophila olfactory and visual systems. PY - 2005 DO - 10.1387/ijdb.041939it VL - 49 IS - 2-3 SP - 201 EP - 207 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/041939it Y2 - 2024/11/21/23:22:56 ER -