TY - JOUR TI - Neural crest derivatives in ocular and periocular structures AU - Creuzet, Sophie AU - Vincent, Christine AU - Couly, Gerard T2 - The International Journal of Developmental Biology AB - In vertebrates, the eye is an ectodermal compound structure associating neurectodermal and placodal anlagen. In addition, it benefits early on from a mesenchymal ectoderm-derived component, the neural crest. In this respect, the construction of chimeras between quail and chick has been a turning point, instrumental in appraising the contribution of the cephalic neural crest to the development of ocular and periocular structures. Given the variety of crest derivatives underscored in the developing eye, this study illustrates the fascinating ability of this unique structure to finely adapt its differentiation to microenvironmental cues. This analysis of neural crest cell contribution to ocular development emphasizes their paramount role to design the anterior segment of the eye, supply refracting media and contribute to the homeostasy of the anterior optic chamber. PY - 2005 DO - 10.1387/ijdb.041937sc VL - 49 IS - 2-3 SP - 161 EP - 171 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/041937sc Y2 - 2024/11/24/15:21:12 ER -