TY  - JOUR
TI  - <I>Pbx </I>genes are required in <I>Xenopus</I> lens development
AU  - Morgan, Richard
AU  - Sohal, Jastinder
AU  - Paleja, Mita
AU  - Pettengell, Ruth
T2  - The International Journal of Developmental Biology
AB  - Development of the vertebrate eye is dependent on multiple tissue interactions and distinct sets of transcription factors and signalling molecules. The latter are thought to be FGF8 and BMP4, proteins secreted from the neural plate to induce lens formation in the overlying ectoderm. Here we show that the Pbx transcription factor plays a crucial role in this process, 
as it is required for FGF8 expression in the neural plate and is thus part of the complex hierarchy of genes involved in lens induction.
PY  - 2004
DO  - 10.1387/ijdb.041887rm
VL  - 48
IS  - 7
SP  - 623
EP  - 627
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/041887rm
Y2  - 2024/11/05/17:21:24
ER  -