TY  - JOUR
TI  - A newt's eye view of lens regeneration 
AU  - Tsonis, PanagiotisA.
AU  - Madhavan, Mayur
AU  - Tancous, EmilyE.
AU  - Del Rio-Tsonis, Katia
T2  - The International Journal of Developmental Biology
AB  - In this paper we describe the basic process of lens regeneration in adult newt and we pinpoint several issues in order to obtain a comprehensive understanding of this ability, which is restricted to only a few salamanders. The process is characterized by dynamic changes in the organization of the extracellular matrix in the eye, re-entering of the cell cycle and dedifferentiation of the dorsal iris pigment epithelial cells. The ability of the dorsal iris to contribute to lens regeneration is discussed in light of iris-specific gene expression as well as in relation to factors present in the eye. 
PY  - 2004
DO  - 10.1387/ijdb.041867pt
VL  - 48
IS  - 8-9
SP  - 975
EP  - 980
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/041867pt
Y2  - 2024/11/05/15:26:23
ER  -