TY - JOUR TI - Pain control by ionizing radiation of bone metastasis AU - Vakaet, LucA.M.-L. AU - Boterberg, Tom T2 - The International Journal of Developmental Biology AB - Pain treatment due to cancer is a large fraction of the care in a radiotherapy department. While radiation treatment is very effective in reducing pain, the pathophysiology of bone metastases remains very complex. Reducing the number of tumour cells by radiation will reduce the pressure in bone marrow, but the very rapid response to radiation treatment seen in some patients is probably related to the presence of highly radiosensitive inflammatory cells. In this review we give an overview of the pathophysiological mechanisms which lead to pain associated with bone metastasis and the impact of radiation treatment and other treatments on this mechanism. PY - 2004 DO - 10.1387/ijdb.041817lv VL - 48 IS - 5-6 SP - 599 EP - 606 J2 - Int. J. Dev. Biol. LA - en SN - 0214-6282 SN - 1696-3547 UR - https://ijdb.ehu.eus/article/041817lv Y2 - 2024/10/11/04:58:20 ER -