TY  - JOUR
TI  - Invasive growth: a genetic program
AU  - Gentile, Alessandra
AU  - Comoglio, PaoloM.
T2  - The International Journal of Developmental Biology
AB  - Invasive growth is defined as a complex biological program which instructs cells 
to dissociate, migrate, degrade the surrounding matrix, proliferate and survive. Together, 
these processes account for tissue morphogenesis, homeostasis and repair, and can be 
aberrantly implemented for cancer dissemination and metastasis. Individual aspects of this process can be controlled by many cytokines and growth factors. However, coordinated regulation of 
invasive growth as a whole is specifically accomplished by Hepatocyte Growth Factor, a soluble factor which acts through the tyrosine kinase receptor Met. Here we discuss the different biological facets of invasive growth and analyze the intracellular signals which lead to its execution.
PY  - 2004
DO  - 10.1387/ijdb.041799ag
VL  - 48
IS  - 5-6
SP  - 451
EP  - 456
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/041799ag
Y2  - 2024/11/21/18:16:25
ER  -