TY  - JOUR
TI  - Embryonic and larval development of NADPH-diaphorase/nitric oxide synthase reactivity in the brain of the amphibian Pleurodeles waltl
AU  - Moreno, N
AU  - Lopez, JM
AU  - Sanchez-Camacho, C
AU  - Crespo, M
AU  - Munoz, M
AU  - Gonzalez, A
T2  - The International Journal of Developmental Biology
AB  - The distribution of NOS-containing cells was studied in the newt Pleurodeles walti during ontogenesis by means of nitric oxyde synthase (NOS) immunochemistry and NADPH-diaphorase histochemistry. Embryonic and larval stages were studied. The first positive neurons were observed at embryonic stage 30 in the ventrolateral area of the caudal rhombencephalon. Subsequently (stage 33b), weakly reactive cells appeared rostrally in the mesencephalic tegmentum, isthmic tegmentum. A general caudorostral gradient of newly expressing NADPHd reactivity cells was observed through larval life. As in the adult, the nitrergic cells in the CNS of the newt are widely distributed during development, pointing to important roles of nitric oxyde through ontogenesis. The sequence of appearance of nitrergic cells revealed a first involvement of this system in reticulospinal control likely influencing locomotor behavior. As development proceeds, cells in different sensory systems express progresively the enzyme NOS in a pattern that shows many similarities with other anamniotes.
PY  - 2001
VL  - 45
IS  - S1
SP  - S81
EP  - S82
J2  - Int. J. Dev. Biol.
LA  - en
SN  - 0214-6282
SN  - 1696-3547
UR  - https://ijdb.ehu.eus/article/01450081
Y2  - 2024/11/05/15:25:24
ER  -